INS and pancreatic neuroendocrine tumor: Two pancreatic NETs pointed out mostly unusual endocrine traits in terms of a growth hormone-releasing hormone (GHRH)-releasing pancreatic NET (with recurrent and metastatic behavior) in a 22-year-old male [117] and, also, in a pediatric subject diagnosed with an insulin-secreting pancreatic NET at the age of 10 which was followed by the confirmation of a GHRH-secreting pancreatic NET at the age of 18 (this represented the first pediatric case with gigantism underlying this specific pathogenic type of GH overproduction) [123].