For instance, a meta-analysis published in 2021 that included 34 studies from inception to 2020 aiming to show the impact of parathyroid tumor removal on metabolic features found no changes in the lipid profile in terms of serum triglycerides, total cholesterol, and LDL (low-density lipoprotein), cholesterol, and HDL (high-density lipoprotein) cholesterol, whereas blood levels of insulin statistically significantly decreased, as well as fasting glucose and systolic and diastolic blood pressure as opposed to the body mass index increase [150]. The gene discussed is INS; the disease is tumor of parathyroid gland.