Multivariate Cox regression analysis (adjusted for tumor stage, lymph node stage, chemotherapy, and molecular subtype) revealed that chemotherapy treatment in all patients with CCL5-negative ICs remained an independent predictor of OS (RR = 0.30; p = 0.006), DSS (RR = 0.36; p = 0.022), and RFS (RR = 0.41; p = 0.046; Table 7) compared to patients who did not receive chemotherapy. The gene discussed is CCL5; the disease is neoplasm.