Carrasco et al. report that ctDNA-detected mutations in TERT and ATM were predictive of tumor progression before radical cystectomy, at four months post-radical cystectomy, and 12 months post-radical cystectomy (HR 6.774, HR 3.673, and HR 30.865, respectively; p < 0.05) [134]. This evidence concerns the gene ATM and neoplasm.