Their reciprocal influence with cellular junctions, such as integrins and E-Cadherin, makes them an interesting factor in the observed differences within the cell proliferation assays, as SRC inhibition was shown to modulate adhesion strength via E-Cadherin in A431 (derived from squamous cell carcinoma) cells and to reduce motility and invasion [26]. The gene discussed is SRC; the disease is squamous cell carcinoma.