FABP4 and cancer: If this is the case, such pseudohypoxia may lead to neovascularization, as was suggested by using an AMD model [30] and malignant tumors [31,32], and this scenario may strongly support our recent proposal that FABP4 is an independent key pathogenic factor for retinal vascular diseases (RVDs) [15] such as DR [9] and RVO [10] in addition to intraocular physiology.