Subsequently, variants in or near SLC16A12, SLC7A8 (14q), which codes for the large neutral amino acids transporter small subunit 2, and SLC24A3 (20p), which codes for the sodium/potassium/calcium exchanger 3, have also been associated with age-related cataract but only SLC24A3 achieved genome-wide significance [55,124,125]. The gene discussed is SLC7A8; the disease is Age-related cataract.