AGK: Soon after loss-of-function mutations in the gene for acylglycerol kinase (AGK) on chromosome 7q were first reported in Sengers syndrome (98% of cases with congenital cataract), a splice-site mutation in AGK, resulting in exon deletion and protein truncation, was linked with isolated autosomal recessive congenital cataract [130]. The gene discussed is AGK; the disease is Sengers syndrome.