SOX3 investigation in different types of cancer: osteosarcoma (OS), breast cancer (BC), gastric cancer (GC), endometrial cancer (EC), esophageal cancer, hepatocellular carcinoma (HCC), lung, ovarian, and acute myeloid leukemia (AML), and its clinical relation with SOX3 expression is summarized and described in Table 1. The gene discussed is SOX3; the disease is osteosarcoma.