For example, in breast cancer cell lines MCF-7 and T-47D, both originating from invasive ductal carcinoma luminal A molecular subtype and characterized by differentiated epithelial cells, a study revealed that miR-483 overexpression, targeting SOX3, induced apoptosis leading to a reduction in cell proliferation (Figure 1A). This evidence concerns the gene SOX3 and invasive ductal breast carcinoma.