Other studies focusing on the TNF-α rs1800629 SNP (−308G/A) have revealed that the G/G ‘low expresser’ genotype was associated with a high risk of adult B-ALL in Sudanese patients, while the −308G/A polymorphism was linked to SLE [64,65] and AML mortality [66]. Here, TNF is linked to systemic lupus erythematosus.