TNF and chronic myelogenous leukemia, BCR-ABL1 positive: This approach allows us to simulate and compute the ratios of the cumulative sum of five cytokines (IL-10, IL-6, IFN-γ, TGF-β1, and TNFα) and to calculate the Kaplan–Meier failure estimate of patients with CML with favorable and unfavorable treatment outcomes in the course of treatment for up to 12 years.