In the context of malignancies, TNFα SNP (−863C/A, −857C/T, −308 G/A, and −238 G/A) was strongly associated with a higher risk of hepatocellular carcinoma (HCC) [33], and the different combinations of SNPs of TNFα (−238G/A or −308G/A) with IL-10 (−592C/A) were highly prevalent among patients with cervical cancer. Here, TNF is linked to hepatocellular carcinoma.