Nuclear factor kappa-B (NF-κB) preferentially binds to +874T allele, perhaps boosting IFN-γ expression and affecting the pathogenesis of tuberculosis [68], and T carriers had statistically increased CML risk in a dominant model (i.e., TT + TA vs. AA) [69]. Here, IFNG is linked to chronic myelogenous leukemia, BCR-ABL1 positive.