PON1 and Hypertension: Specifically, after adjusting for age and hypertension, the <i>PON1</i> 192 R allele (QR + RR) was found to be associated with a statistically significantly higher risk of RVO compared to the QQ genotype (OR = 2.51; 95% CI = 1.02-6.14, <i>p</i> = 0.04).