Pathogenic variants in the <i>FKBP10</i> gene lead to a spectrum of rare autosomal recessive phenotypes, including osteogenesis imperfecta (OI) Type XI, Bruck syndrome Type I (BS I), and the congenital arthrogryposis-like phenotype (AG), each with variable clinical manifestations that are crucial for diagnosis. The gene discussed is FKBP10; the disease is osteogenesis imperfecta.