VEGFA and Castleman-Kojima disease: Lee et al. (2020) recently conducted a systematic literature review of 66 iMCD patients regarding the role of VEGF in the pathogenesis of TAFRO syndrome and found support for a role of VEGF-A in TAFRO, with fibroblastic reticular cells (FRCs) as the likely pathological VEGF-A-expressing cells [23].