HOXB7 expression was analyzed and compared with that of five patients with no evidence of pulmonary fibrosis as controls.<h4>Results</h4>The semi-quantitative analysis of IHC showed that HOXB7 protein expression was higher in IPF patients compared to controls (difference between means = 6.2 ± 2.37, <i>p</i> = 0.0157). This evidence concerns the gene HOXB7 and idiopathic pulmonary fibrosis.