The significance level for the analysis was set at 5%.<h4>Results</h4>Women with SO who have higher levels of PAI-1 have lower values of high-density lipoprotein cholesterol (HDL) (<i>p</i> = 0.037) and QUICKI (0.020) and higher values of HOMA-AD (0.046) and HOMA-IR (0.037). The gene discussed is SERPINE1; the disease is Alzheimer disease.