In contrast, Schamberger et al. reported that GPX3 was upregulated in lung homogenates from IPF patients and in mouse bronchoalveolar lavage fluid (BALF) during bleomycin-induced lung fibrosis, suggesting that GPX3 is expressed by bronchial epithelial cells and secreted in its active form into the epithelial lining fluid [103]. This evidence concerns the gene GPX3 and idiopathic pulmonary fibrosis.