Cirrhosis (secondary to hepatitis induced by HBV, HCV, or other etiologies) is characterized by liver regeneration, leading to the stimulation of hepatocyte proliferation through the upregulation of HGF and/or c-MET, as well as inflammation and fibrosis through c-MET activation (reducing inflammation and stimulating fibrogenesis). The gene discussed is MET; the disease is Cirrhosis.