PPARGC1A and gastric cancer: In MDR GC cell lines, MSCs were found to secret exosomes containing HCP5 to confer chemo-resistance and enhance the FAO-dependent stemness of GC cells by adsorbing miR-3619-5p to increase PPARGC1A expression, finally leading to the transactivation of CPT1 by the PGC1α/CEBPB complex [55].