A number of IFIH1 polymorphisms were linked with T1DM, especially the rs1990760 (G/A) polymorphism in the United Kingdom population (substitution of an alanine for a valine in codon 946 of exon 15) being most closely linked with protection from disease development (OR = 0.86, p = 1.42 × 10−10 for the G allele) [42]. The gene discussed is IFIH1; the disease is type 1 diabetes mellitus.