The rs55703767 is a common missense variant in exon 17 of COL4A3. This variant’s risk allele impacted the risk of macroalbuminuria or end-stage renal disease, and its frequency was prevalent among Europeans (20%) and East Asians (13%), but modest in Africans (2%) [62]. This evidence concerns the gene COL4A3 and stage 5 chronic kidney disease.