Although there are no significant differences for the Iba-1 signal between the VEH and CBD groups, in the case of VEH this may be due to the extreme necrosis of the tissue demonstrated by the grade 3 NEC damage (Fig. 3) and the apoptotic death of the tissue demonstrated by the TUNEL technique (Fig. 4A). This evidence concerns the gene AIF1 and necrotizing enterocolitis.