ERBB2 and neoplasm: The biomolecular characteristics of the surgical sample displayed a locally advanced primitive tumour at stage T4b (pTy4b) with involvement of regional lymph nodes (pNy2a) and absence of distant metastasis (pM0); oestrogen receptor 90%, progesterone receptor < 2%, Ki67 20%, and HER2 1+. After the surgery, the patient was treated with locoregional radiotherapy to the left chest wall and ipsilateral clavicular region (dose of 50.4 Gray in 28 fractions with 3D conformal technique).