Accordingly, it is reported that FADS expression and activity determine ferroptosis sensitivity in gastric and ovarian cancer (Lee et al, 2020; Xuan et al, 2022), whereas those of SCD sustain ferroptosis resistance in breast cancer (Luis et al, 2021), reinforcing the idea that PUFA intracellular availability is necessary for ferroptosis execution. This evidence concerns the gene SCD and ovarian cancer.