Furthermore, we confirmed the translation expression level of the hub genes using the HPA database, and the prognostic biomarkers were found to be stained strongly or moderately.: SMC4 (Fig. 9A), OCR1 (Fig. 9B), CDCA8 (Fig. 9C), and DLGAP5 (Fig. 9D), indicating that these hub genes were translated more in glioma samples. This evidence concerns the gene SMC4 and glioma.