In line with this—CCL5, a chemoattractant for monocytes and T cells15—was only increased in Kmt2c but not Kmt2d KO cell supernatants and tumours, whereas CXCL1 and matrix metalloproteinase 3 (MMP3) were higher in all KO samples (Extended Data Fig. 2o). Here, CXCL1 is linked to neoplasm.