TGFB1 and dilated cardiomyopathy: Comparing to IR group, Gene Set Enrichment Analysis (GSEA) identified significant negative association between the GluCARDIA-siIRF3 treatment and signaling pathways related to transforming growth factor β (TGF-β) signaling pathway (Fig. 7b) and dilated cardiomyopathy (Supplementary Fig. 12a)51, indicating a potentially better prognosis regarding to LV remodeling.