To investigate the relationship between CRT and EMT in CRC patients, Kawamoto et al. [46] measured the expression levels of epithelial markers (CDH1), interstitial markers (VIM, FN1), and EMT-related transcription factors (SNAI1, SNAI2, TWIST1) in 26 rectal cancer patients pre- and post-NCRT. This evidence concerns the gene SNAI2 and rectal cancer.