For example, SNORD1C was shown to maintain stemness and chemoresistance by activating the Wnt signaling pathway in CRC.[10] SNORD33 is downregulated in CRC and functions as a tumor suppressor.[33] While the role of snoRNAs in regulating tumor cell growth and chemotherapy resistance is now well‐established,[10, 14] their influence on radiosensitivity has rarely been studied. The gene discussed is SNORD33; the disease is colorectal carcinoma.