Through the profiling of PC patient cohort dataset in the database UALCAN, S100A16 expression was also significantly elevated in PC tumour tissues when compared to normal tissues (Figure 5D) and the relative levels of S100A16 were higher in Grade 2 and 3 tumour samples when compared to Grade 1 samples (Figure 5E). This evidence concerns the gene S100A16 and pachyonychia congenita.