Two previous studies reported no difference in ISIMatsuda following 6 weeks (180 min/week, 60%–65% V ̇O2peak) and 10 weeks (90 min per week, 70% V ̇O2peak) of upper‐body MICT despite significant reductions in fasting insulin and HOMA–insulin resistance (HOMA‐IR) (Bresnahan et al., 2019; Nightingale, Walhin et al., 2017). Here, INS is linked to Insulin resistance.