PIEZO1 and Cognitive impairment: The upregulation and activation of microglial Piezo1 serve as a protective process against Aβ pathology, because the Piezo1‐activated microglia expresses a high level of genes associated with innate immune response and cytoskeleton dynamics, which introduce the phagocytosis of Aβ and microglial migration, and subsequently result in alleviating Aβ accumulation and cognitive impairment.96, 109