Blood tests were remarkable for severely impaired kidney function (urea 286 mg/dL, creatinine 4 mg/dL, 2021 CKD‐EPI eGFR 17 mL/min/1.73 m2), iron deficiency anemia (hemoglobin 11 g/dL, ferritin 67.8 ng/mL, transferrin saturation 12%), hypoalbuminemia (albumin 3.1 g/dL), and elevated brain natriuretic peptide (BNP 3283 pg/mL), while electrolytes, liver, and thyroid function tests, arterial blood gas, cardiac enzymes, and inflammatory markers were all within normal range (Table 1). This evidence concerns the gene NPPB and chronic kidney disease.