The KEGG results revealed correlations between endothelial cells and the downregulation of activities associated with allograft rejection, processing and presentation, autoimmune thyroid disease, fatty acid metabolism, glycolysis gluconeogenesis, leishmania infection, P450 metabolism of xenobiotics by cytochrome and retinol metabolism (Figure 2A). The gene discussed is CYP2B6; the disease is autoimmune thyroid disease.