Furthermore, based on the expression of SERPINC1, we divided the colon cancer patients in GSE39582 into two groups with high and low expression of SERPINC1 according to the expression of SERPINC1, and performed enrichment analysis for the differential genes between the two groups, SERPINC1 was strongly associated with metastasis of colon cancer cells (additional Figure 1). Here, SERPINC1 is linked to malignant colon neoplasm.