The top gene alterations in HER2‐mutant NSCLC including TP53, SETD2, PTPRT, PBRM1, KMT2C, GRIN2A, DNMT3B, ZFHX3, TET2, TERT, RBM10, RB1, PTPRD, PPP2R1A, POLE, PIK3R2, PIK3CA, PDGFRB (Figure 4C). This evidence concerns the gene DNMT3B and non-small cell lung carcinoma.