A paper conducted to evaluate the expression of the chemokine receptor, CXCR6 in human colorectal adenocarcinomas showed that CXCR6 can increase the number of antigen-presenting cells in the mucosa and the down-regulation of CXCR6 found in tumor tissue may be a tactic used by tumors to avoid conflict with leukocytes that have infiltrated the tumor, such as antigen-presenting cells. This evidence concerns the gene CXCR6 and neoplasm.