BRAF and colorectal carcinoma: In contrast, the B-Raf proto-oncogene, serine/threonine kinase (BRAF) mutation and neurotrophic tyrosine receptor kinase (NTRK) gene fusion have been identified as prevalent in MSI-H/dMMR CRC, whereas these alterations are not enriched in MSI-H/dMMR GC [2, 32, 136].