SOD1 and familial amyotrophic lateral sclerosis: Another interesting study investigated whether ASC-Exo could protect motoneuron-like NSC-34 cells from oxidative damage, as well as an in vitro model of familial amyotrophic lateral sclerosis (fALS) (NSC-34 SOD1(G93A); NSC-34 SOD1(G37R); NSC-34 SOD1(A4V)) [200].