Cheng et al., for example, reported that the LTL of essential hypertension patients was significantly shorter, which might be due to the defective TERT (telomerase reverse transcriptase) and TERC (internal RNA template) expression in leukocytes, which is responsible for maintaining and prolonging LTL and plays a role in regulating tissue repair and regeneration [43]. This evidence concerns the gene TERC and hypertensive disorder.