TNF-α and IL-10, molecules involved in the amplification of the inflammatory response, in the control of the Th1/Th2 balance, and which, in leprosy patients, have an important role in the different forms and reactional states [56,57], in hOSEC had their expression rates reduced by viable bacilli and increased by dead bacilli, compared to skin without bacilli. Here, TNF is linked to leprosy.