Consequently, it is speculated that in A. cantonensis infected mice, leading to eosinophilic meningoencephalitis, MβCD can negatively regulate Cav-1, subsequently degrading tight junction proteins of the TLR4/MyD88 signaling pathway, thus altering the permeability of the BBB and ultimately contributing to cerebral hemorrhage and cerebral edema. The gene discussed is MYD88; the disease is brain edema.