High-level activation of oncogenes (e.g. KRAS, BRAF, and c-MYC) triggers intrinsic tumor suppression (Bennecke et al., 2010; Michaloglou et al., 2005; Dankort et al., 2007; Sarkisian et al., 2007; Murphy et al., 2008). This evidence concerns the gene KRAS and neoplasm.