In another coevolution study, Borin and colleagues incubated populations of E. coli B strain REL606 with λ phages in flasks for 30 days at MOI 104 or 103, which were either untrained lytic strains that use LamB as a receptor or trained lytic strains that may use two receptors for infection, namely, LamB or OmpF. The gene discussed is GRAMD1B; the disease is infection.