Particularly, irf3 FC values were 47.59 and 26.43 at 3 and 7 days after infection with DlNNV, respectively; these values were significantly lower (p < 0.05) than those reported in fish injected with the reassortant isolate (78.45 and 74.40 mean FC values at 3 and 7 dpi, respectively) (Figure 3). The gene discussed is IRF3; the disease is infection.