Considering both the ceRNA network and the hub genes analyzed by PPI and WGCNA, four mRNAs (FBN1, COL1A1, COL5A1, BGN) and two lncRNAs (XIST, LINC00173) were identified, and we speculated that the six nodes were potential biomarkers associated with ARVC. The gene discussed is COL1A1; the disease is Arrhythmogenic right ventricular dysplasia.