C3 and glomerulosclerosis: Likewise, Bulucu et al. [23] described the case of a 40-year-old patient with renal involvement and IHES, whose RB showed glomerular sclerosis with periglomerular fibrosis, mild mesangial proliferation, and infiltration of eosinophils, with deposits of IgG, IgM, IgA, and C3.