Likewise, Bulucu et al. [23] described the case of a 40-year-old patient with renal involvement and IHES, whose RB showed glomerular sclerosis with periglomerular fibrosis, mild mesangial proliferation, and infiltration of eosinophils, with deposits of IgG, IgM, IgA, and C3. Here, CD40LG is linked to glomerulosclerosis.