In lean NASH-HCC (CHCHD2, FSCN1, ZDHHC12, PNPLA6, LDLRAP1);In obese NASH-HCC (RNF217, GJA8, PTPRE, PSAPL1, LRRC8D). The gene discussed is CHCHD2; the disease is metabolic dysfunction-associated steatohepatitis.