OTC and Nijmegen breakage syndrome: However, CKD1 and CKD2/3 have a similar expression pattern compared to CKD0 for other indicators such as medium-chain acyl-coenzyme A dehydrogenase (MCAD) deficiency (NBS), ornithine transcarbamylase (OTC) deficiency (NBS), 1-Met-His synthesis, sum of diacyl-phosphatidylcholines (PCs (aa)), sum of acyl-alkyl-phosphatidylcholines (PCs (ae)), and sum of indoles.