These CHs exert anti-inflammatory, anti-angiogenesis, apoptosis, and cell cycle arrest activities in cancer cells through a wide range of molecular mechanisms such as cyclin-dependent kinase 1 (CDK1), proliferating cell nuclear antigen (PCNA), and nuclear transcription factor kappaB (NFκB) [17,18,19,20,21,22]. Here, PCNA is linked to cancer.