Both nitrosamines (NNK, NNN) and nicotine demonstrated significant induction of the nicotinic acetylcholine receptor (α7nAChRs) and beta-adrenergic receptor (β-AdrR) expressed in several brain areas (e.g., hypothalamus), which could, in turn, promote tumor growth, proliferation, angiogenesis, and metastasis in NSCLC cells [4,5,6]. This evidence concerns the gene CHRNA7 and non-small cell lung carcinoma.