CHRNA7 and neoplasm: In vitro and/or in vivo experiments have shown that licorice CHs exert multiple therapeutic effects in nicotine-induced NSCLC, including anti-proliferative, anti-tumor growth, anti-invasion, anti-migration, anti-viability, apoptosis, cell cycle arrest, and autophagy through modulating α7nAChR-mediated signaling pathways and molecular genes.