On the other hand, a number of other comprehensive reviews on apoptosis in cancer [37,38,39,40,41,42] and related topics (e.g., p53-based therapies [43,44,45,46,47], synthetic “lethality” [48,49,50,51,52,53,54]) have been recently published in high impact factor journals that completely ignore the dark side of apoptosis in cancer therapy. This evidence concerns the gene TP53 and cancer.