From these studies, Li et al., 2020 [74] found an increase in the expression of MALAT1 in gingival biopsies derived from patients with periodontitis stage III grade C. Similarly, Chen et al., 2019 [77] also concluded that MALAT1 was upregulated in periodontal ligament cells from chronic periodontitis patients. Here, MALAT1 is linked to chronic periodontitis.