Three key characteristics of dendritic cells (DCs) are essential for eliciting a robust and sustained antitumor response: effective migration between lymphoid and non-lymphoid tissues, cross-presentation of tumor-associated antigens (TAAs) to CD8+ cytotoxic T lymphocytes to initiate strong effector responses against the tumor, and the release of chemokines and cytokines to regulate the overall immune response and T-cell homing [114]. Here, CD8A is linked to neoplasm.