Pathways relating to TGFβ signalling, MAPK signalling, PI3K-Akt signalling, Hippo signalling, Wnt signalling, focal adhesion, and regulation of the actin cytoskeleton are relevant to glaucoma/PXFG pathogenesis and are listed in Table S2 (significantly up-regulated miRNAs) and Table S3 (significantly down-regulated miRNAs) along with the associated miRNAs and gene targets. This evidence concerns the gene AKT1 and glaucoma.